Chromosomal aneuploidy in embryos (an incorrect number of chromosomes) is one of the main causes of IVF treatment failure and miscarriage.
At Northway Clinic, the most advanced NGS (Next-Generation Sequencing) method is offered for embryo genetic testing. This technology uses the latest human genome sequencing techniques (direct reading of genetic information), opening up new diagnostic possibilities. Compared with earlier methods, which had limitations in scope and accuracy, NGS allows analysis of all 24 chromosomes and provides 99.99% accuracy.
Preimplantation genetic testing helps select the most suitable embryo for transfer to the uterus and can significantly increase the chances of a successful procedure and the birth of a healthy child.
Indications for NGS testing:
- The woman is over 35 years of age.
- Multiple unsuccessful IVF cycles.
- Recurrent miscarriages.
- Genetic abnormalities diagnosed during a previous pregnancy.
- Increased genetic risk in the family (chromosomal abnormalities, inherited diseases).
PGS using the NGS method:
- IVF/ICSI – The assisted fertilization procedure is performed.
- Biopsy – A small sample of cells is taken from the outer layer of a day-5 embryo.
- Tubing – The collected cell sample is placed in a small tube and sent to the laboratory.
- Testing – The cells are analyzed to determine whether the embryo is genetically normal.
- Results – Test results are received within 7–14 days.